ZOETIS INC.
333 PORTAGE STREET, KALAMAZOO, MI, 49007
Telephone: 269-359-4414
Customer Service: 888-963-8471
Website: www.zoetis.com
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.
QUEST® GEL
Zoetis
(moxidectin)
2% Equine Oral Gel
Contains 20 mg moxidectin/mL (2.0% w/v)
DEWORMER & BOTICIDE
FOR ORAL USE IN HORSES AND PONIES SIX MONTHS OF AGE AND OLDER
INDICATIONS
QUEST (moxidectin) 2% Equine Oral Gel when administered at the recommended dose level of 0.4 mg moxidectin/kg (2.2 lb) body weight is effective in the treatment and control of the following stages of gastrointestinal parasites in horses and ponies:
Large Strongyles:
Strongylus vulgaris - (adults and L4/L5 arterial stages)
Strongylus edentatus - (adults and tissue stages)
Triodontophorus brevicauda - (adults)
Triodontophorus serratus - (adults)
Small Strongyles (adults):
Cyathostomum spp., including
Cyathostomum catinatum
Cyathostomum pateratum
Cylicostephanus spp., including
Cylicostephanus calicatus
Cylicostephanus goldi
Cylicostephanus longibursatus
Cylicostephanus minutus
Cylicocyclus spp., including
Cylicocyclus insigne
Cylicocyclus leptostomum
Cylicocyclus nassatus
Cylicocyclus radiatus
Coronocyclus spp., including
Coronocyclus coronatus
Coronocyclus labiatus
Coronocyclus labratus
Gyalocephalus capitatus
Petrovinema poculatus
Small Strongyles:
Undifferentiated lumenal larvae
Encysted cyathostomes:
Late L3 and L4 mucosal cyathostome larvae
Ascarids:
Parascaris equorum - (adults and L4 larval stages)
Pinworms:
Oxyuris equi - (adults and L4 larval stages)
Hairworms:
Trichostrongylus axei - (adults)
Large-mouth stomach worms:
Habronema muscae - (adults)
Horse stomach bots:
Gasterophilus intestinalis - (2nd and 3rd instars)
Gasterophilus nasalis - (3rd instars)
One administration of the recommended dose rate of QUEST (moxidectin) 2% Equine Oral Gel also suppresses strongyle egg production through 84 days. QUEST is indicated for use in horses and ponies, including breeding mares and stallions, and foals six months of age and older.
STRATEGIC PROTECTION PROGRAMS
Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. For best control of parasites, all horses and ponies should be included in a strategic treatment program, with particular attention given to high performance animals, brood mares, stallions and foals. In foals, initial treatment is recommended at 6 months of age, after which they should be included in a recurrent treatment program. Because QUEST provides effective control of the mucosal stages of small strongyles (encysted cyathostomes), it is useful in reducing the frequency of treatment required for successful strategic equine parasite control. A veterinarian can assist in preparing the best program for your needs.
QUEST 2% Equine Oral Gel when used at the recommended dose rate suppresses strongyle egg production through 84 days following a single oral administration. This residual strongyle control reduces pasture contamination and provides a period of protection from reinfection for horses and ponies maintained on the same pasture.
MODE OF ACTION
QUEST 2% Equine Oral Gel acts by interfering with chloride channel-mediated neurotransmission in the parasite. This results in paralysis and elimination of the parasite. Moxidectin is safe for use in horses and ponies because it does not have the same injurious effect on the mammalian nervous system.
ADMINISTRATION AND DOSAGE
QUEST (moxidectin) 2% Equine Oral Gel is specially formulated as a palatable gel which is easily administered to horses and ponies. QUEST Gel is packaged in ready-to-use SURE-DIAL® syringes. The syringe is calibrated in 50-pound increments, up to 1500 pounds. This enables the administration of the recommended dose level of 0.4 mg moxidectin/kg body weight by choosing a setting consistent with the animal’s weight.
Do not underdose. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineffective treatment, and encourage the development of parasite resistance.
HOW TO SET THE DOSE
Since the dose is based on the weight of the animal, you need to use a scale or weight tape to find each animal’s weight before treating with QUEST Gel. Once the weight is known, set the dose for each horse or pony as follows.
1. Hold the syringe with the capped end pointing to the left and so that you can see the weight measurements and tick marks (small black lines). Each tick mark relates to 50 lb of body weight.
2. Turn the white dial ring until the left side of the ring lines up with the weight of the animal. In the diagram below, the dial ring is set to dose a 500 lb animal.
HOW TO GIVE QUEST GEL TO A HORSE OR PONY
1. Make sure there is no feed in the animal’s mouth.
2. Remove the cap from the end of the syringe. Save the cap for reuse.
3. Place the tip of the syringe inside the animal’s mouth at the space between the teeth.
4. Gently push the plunger until it stops, depositing the gel on the back of the tongue.
5. Remove the syringe from the animal’s mouth and raise the animal’s head slightly to make sure it swallows the gel.
6. Replace the syringe cap.
TREATING A SECOND HORSE OR PONY WITH THE SAME SYRINGE
If the first animal you treat weighs less than 1500 lb, there will be gel left in the syringe. You can use this gel to treat other horses or ponies. To set the next dose, add the weight of the animal you want to treat to the dose setting already on the syringe. For example, if the syringe was first used to treat a 250 lb animal, the white dial ring is set on 250 lb. To treat a 500 lb animal next, move the white dial ring to the 750 lb marking (250+500=750). You need more than one syringe to treat horses weighing more than 1500 lb.
ANIMAL SAFETY
QUEST (moxidectin) 2% Equine Oral Gel can be safely administered at the recommended dose of 0.4 mg moxidectin/kg body weight to horses and ponies of all breeds at least 6 months of age or older. Transient depression, ataxia and recumbency may be seen when very young or debilitated animals are treated. In these instances, supportive care may be advisable.
Reproductive safety studies demonstrate a wide margin of safety when the product is used in the treatment of estrual and pregnant mares and breeding stallions.
To report adverse drug reactions or to obtain a copy of the Safety Data Sheet (SDS) call 1-888-963-8471.
ENVIRONMENTAL SAFETY
Care should be taken to avoid the release of significant volumes of moxidectin into either ground or free-running water since moxidectin may be injurious to aquatic life. SURE-DIAL® syringes and their contents should be disposed of in an approved landfill or by incineration.
PRECAUTIONS:
QUEST 2% Equine Oral Gel has been formulated specifically for use in horses and ponies only. This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result.
WARNINGS
Extreme caution should be used when administering the product to foals, young and miniature horses, as overdosage may result in serious adverse reactions. Do not use in sick, debilitated, or underweight animals. Do not use in horses intended for human consumption.
HUMAN WARNINGS
Not for use in humans. Keep this and all drugs out of the reach of children. Do not ingest. If swallowed, induce vomiting. Wash hands and contaminated skin with soap and water. If accidental contact with eyes occurs, flush repeatedly with water. If irritation or any other symptom attributable to exposure to this product persists, consult your physician.
OTHER WARNINGS
Parasite resistance may develop to any dewormer, and has been reported for most classes of dewormers. Treatment with a dewormer used in conjunction with parasite management practices appropriate to the geographic area and the animal(s) to be treated may slow the development of parasite resistance. Fecal examinations or other diagnostic tests and parasite management history should be used to determine if the product is appropriate for the herd prior to the use of any dewormer. Following the use of any dewormer, effectiveness of treatment should be monitored (for example, with the use of a fecal egg count reduction test or another appropriate method). A decrease in a drug’s effectiveness over time as calculated by fecal egg count reduction tests may indicate the development of resistance to the dewormer administered. Your parasite management plan should be adjusted accordingly based on regular monitoring.
HOW SUPPLIED
QUEST 2% Equine Oral Gel is available in one syringe applicator size. Each SURE-DIAL® syringe contains 0.5 oz (14.4 g) of QUEST 2% Equine Oral Gel which is sufficient to treat a single horse weighing up to 1500 lb, or two or more lighter animals with a combined body weight of up to 1500 lb.
0.5 oz (14.4 g) syringe - 20 mg moxidectin per mL
Available in 45-pack bulk.
Store at or below 77°F (25°C). Avoid freezing. If frozen, thaw completely before use. Store partially-used syringes with the cap tightly secured.
Approved by FDA under NADA # 141-087
Manufactured by: Zoetis Manufacturing and Research Spain, S.L., Girona, Spain
Distributed by: Zoetis Inc., Kalamazoo, MI 49007
Revised: May 2019
40027695
CPN: 3690353.3
