Pyramid® 5 is used for the vaccination of healthy cattle as an aid in the prevention of disease caused by bovine rhinotracheitis virus, bovine virus diarrhea (types 1 and 2), bovine parainfluenza 3, and bovine respiratory syncytial virus. This product aids in the prevention of persistent BVD Type 1 and Type 2 infection of the fetal calf when it is used subcutaneously in the cow or heifer 30-60 days pre-breeding. This vaccine may be used in pregnant cows or calves nursing pregnant cows, provided the cows were vaccinated pre-breeding, according to label instructions, with Pyramid® 5, Pyramid® 10 or Pyramid® 3.
This product also aids in the prevention of persistent BVD Type I and Type II infection in fetal calves when used subcutaneously in cow or heifer 30-60 days pre-breeding. May be used in pregnant cows or calves nursing pregnant cows, provided the cows were vaccinated pre-breeding, according to label instructions, with Pyramid® 5, Pyramid® 10 or Pyramid® 2 + Type II BVD. This product contains BVD Types I and II.
Modified-live virus for vaccination of healthy cattle as an aid in the prevention of disease caused by IBR, BVD Types 1 & 2, PI3 and BRSV. A DOI of 217 days has been demonstrated against respiratory disease caused by BVD Type 1b. Vaccination provides a protective effect against development of post-challenge viremia and leukopenia. Also aids in the prevention of persistent BVD Types 1 & 2 infection of the fetal calf when used subcut in the cow or heifer 30-60 days pre-breeding. May be used in pregnant cows or calves nursing pregnant cows provided cows were vaccinated pre-breeding, according to label instructions, with any Express FP vaccine, Pyramid 5, Pyramid 10 or Pyramid 5 + Presponse SQ.
Store out of direct sunlight at 35-46°F (2-8°C). Do not freeze. Do not mix with other products, except as specified on the label. Use entire contents when first opened. Do not vaccinate within 21 days before slaughter. A small percentage of animals may show transient mild injection site swelling. In case of anaphylactoid reaction, administer epinephrine. In case of human exposure, contact a physician. Inactivate unused contents before disposal.
Cattle: inject 2 mL dose subcutaneously using aseptic technique. Protect animals from exposure for at least 14 days after vaccination. Calves vaccinated under 6 months of age should be revaccinated at 6 months of age. Healthy cattle should be vaccinated at a minimum of 14 days prior to shipping or exposure to stress, which may precipitate infectious conditions.
Manufacturer and/or Label Information
Manufacturer and/or Label Information
GENERAL INFORMATION: This product has been shown to be effective for the vaccination of healthy horses, cattle, sheep, goats, and swine against tetanus. This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.
Safety in pregnant animals is unknown.
Tetanus Toxoid is prepared by detoxifying tetanus toxin in such a manner as to allow the antigenic properties to remain intact. Product is purified, concentrated and adjuvanted to provide a low dose effective immunizing agent.
Each serial is tested for purity, safety, and potency in accordance with USDA requirements.
Tetanus is caused by a neurotoxin produced by growth of Clostridium tetani, an anaerobic (lives without air) micro-organism, in necrotic tissue. Affected animals become stiff, have difficulty swallowing, and have an increased pulse rate. Breathing is labored. Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw.
Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw. Thus, the term “lockjaw” is often used. Legs and tail are often stiff with abdominal muscles contracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.
Protective antibody levels usually occur about two weeks after the second injection of the primary immunization series. In contrast, administration of Tetanus Antitoxin is recommended for immediate, emergency, passive treatment of exposed animals with unknown vaccination history or with signs of tetanus infection.
DIRECTIONS: Do not vaccinate within 21 days before slaughter. Store at 2-8° C. Do not freeze. Do not mix with other products. Shake well before use. Use entire contents when first opened.
PRECAUTIONS: A transitory local reaction may occur at injection site. Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. In case of human exposure, consult a physician.
DOSAGE & ADMINISTRATION: For primary immunization, two doses should be administered subcutaneously or intramuscularly approximately 30 days apart. Use intramuscularly for horses as local reactions are more likely to occur if injected subcutaneously.
Horses: 1 ml IM
Cattle: 1 ml SC or IM
Sheep, Goats, Swine: 0.5 ml SC or IM
Historically, annual single dose revaccination has been recommended. Contact veterinarian for advice.
OTHER INFORMATION: Contains thimerosal and formalin as preservatives. Tetanus Toxoid Concentrate is available in single dose size packaged 10 vials to the carton, and in 10 dose vials.
THE PEAK OF QUALITY SINCE 1923
VLN: 188 / PCN: 8601.00
COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216
Contact us for information on other Colorado Serum Company products. Fine Veterinary Products since 1923.
FOR VETERINARY USE ONLY
10 - 1 ml vials
10 - 1 dose vials
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