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Merck Animal Health

ProSystem Rota-50 Dose

ProSystem Rota-50 Dose

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Modified-live virus for use as an aid in the prevention of Rotavirus in baby pigs.

An aid in the prevention of rotaviral diarrhea in young piglets, a 1 mL oral dose and 1 mL IM dose to pig preweaning. Unique rotavirus protection includes two major serotypes G4 and G5 of Serogroup A. Freeze dried MLV vaccine with diluent. Greatly reduces the incidence and severity of rotavirus scours in young pigs. First USDA licensed vaccine with two serotypes of serogroup A rotavirus, G5 (A1) and G4 (A2), for best protection. Aids in the control of rotaviral diarrhea in weaned pigs. Extensively evaluated in experimental tests and field trials. Proven safe for preweaned pigs by oral and IM route. 100% protection from
mortality in rotavirus challenge of vaccinated piglets. For use as an aid in the prevention of rotavirus diarrhea in young pigs, contains two major rotavirus serotypes.

Dosage: 1 ml orally and 1 ml IM about 7-10 days before weaning. Do not return baby pig to sow for at least 30 minutes after oral vaccination. 21-day slaughter withdrawal. 
Size: 50 dose 

Manufacturer and/or Label Information

Intervet Inc.
Customer Service: 800-521-5767
Order Desk: 800-648-2118
Technical Service (Companion Animal): 800-224-5318
Technical Service (Livestock): 800-211-3573
Fax: 973-937-5557
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.
ProSystem® Rota

Intervet/Merck Animal Health

Porcine Rotavirus Vaccine

Modified Live Virus

Porcine Rotavirus Vaccine is a modified live virus containing 2 modified live G serotypes 5 and 4 of Serogroup A rotavirus, which have been modified so that they do not cause disease in baby pigs, feeder pigs or pregnant swine. The vaccine is recommended as an aid in the prevention of rotaviral diarrhea in young pigs. Rotavirus is one cause of viral gastroenteritis characterized by vomiting, watery diarrhea, dehydration and death in young pigs; therefore, the clinical signs may be identical to those of TGE. The disease is very common in both nursing and weaned pigs, and all swine herds so far examined show serologic evidence of its presence. Efficacy of the rotavirus vaccine has been demonstrated in both pregnant sows and baby pigs. Some animals may be unable to develop or maintain an adequate immune response following vaccination if they are incubating any infectious disease, are malnourished or parasitized, or stressed due to shipment or adverse environmental conditions. Oral and intramuscular vaccination of nursing pigs induces active immunity and will protect them against post-weaning rotavirus-induced scours. Laboratory confirmation of the cause of baby pig diarrhea is recommended since other viral, bacterial and coccidial agents can cause similar disease signs. If diarrhea persists after use of the vaccine, additional diagnostic work may be warranted.

INDICATIONS: For use as an aid in the prevention of rotavirus diarrhea in young pigs. Contains two major Rotavirus serotypes. It is recommended that pregnant sows and gilts always be vaccinated with ProSystem® TGE/Rota (Porcine Rotavirus-Transmissible Gastroenteritis Vaccine) (as directed) prior to farrowing. This should result in increased levels of milk antibody and protection of nursing pigs. Since pigs lose their passive milk protection when they are weaned, it is necessary to actively immunize them by oral and intramuscular vaccination prior to weaning.

Dosage and Directions:

Vaccinate each baby pig with one 1 mL oral dose and one 1 mL intramuscular dose about 7-10 days preweaning.

Reconstitute desiccated virus vaccine with sterile diluent provided using 10-15 mL. Then transfer all liquid vaccine to the 50 mL plastic diluent vial to obtain 50 doses of 1 mL each.

Vaccine can then be administered with either automatic syringes or a plastic oral dosing bottle.

Inoculate each pig orally with 1 mL of the reconstituted ProSystem® Rota vaccine and inject one dose intramuscularly.

Do not return the pig to the sow for at least 30 minutes after oral vaccination.

Always wash oral vaccine dispensers thoroughly with soap and water and rinse thoroughly with clean water before addition of vaccine.

CAUTION: Store in the dark at 2° to 7°C (35° to 45°F). Do not freeze. Use immediately after reconstitution; do not save partial contents; burn both containers and all unused contents. Use only in healthy animals. Do not vaccinate within 21 days of slaughter. If allergic reaction occurs, treat with epinephrine. Contains gentamicin as preservative.


Intervet Inc., Merck Animal Health, division of Intervet Inc., Omaha, NE 68103 USA

U.S. Veterinary License No. 165A


For patent information:


50 doses

50 mL



CPN: 1047364.3

COLORADO SERUM COMPANY4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428Telephone: 303-295-7527Order Desk: 800-525-2065Fax: 303-295-1923Website: www.colorado-serum.comEmail: colorado-serum@colorado-serum.comTHIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.


Colorado Serum


GENERAL INFORMATION: This product has been shown to be effective for the vaccination of healthy horses, cattle, sheep, goats, and swine against tetanus. This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. For more information regarding efficacy and safety data, see

Safety in pregnant animals is unknown.

Tetanus Toxoid is prepared by detoxifying tetanus toxin in such a manner as to allow the antigenic properties to remain intact. Product is purified, concentrated and adjuvanted to provide a low dose effective immunizing agent.

Each serial is tested for purity, safety, and potency in accordance with USDA requirements.

Tetanus is caused by a neurotoxin produced by growth of Clostridium tetani, an anaerobic (lives without air) micro-organism, in necrotic tissue. Affected animals become stiff, have difficulty swallowing, and have an increased pulse rate. Breathing is labored. Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw.

Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw. Thus, the term “lockjaw” is often used. Legs and tail are often stiff with abdominal muscles contracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.

Protective antibody levels usually occur about two weeks after the second injection of the primary immunization series. In contrast, administration of Tetanus Antitoxin is recommended for immediate, emergency, passive treatment of exposed animals with unknown vaccination history or with signs of tetanus infection.

DIRECTIONS: Do not vaccinate within 21 days before slaughter. Store at 2-8° C. Do not freeze. Do not mix with other products. Shake well before use. Use entire contents when first opened.

PRECAUTIONS: A transitory local reaction may occur at injection site. Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. In case of human exposure, consult a physician.

DOSAGE & ADMINISTRATION: For primary immunization, two doses should be administered subcutaneously or intramuscularly approximately 30 days apart. Use intramuscularly for horses as local reactions are more likely to occur if injected subcutaneously.

Horses: 1 ml IM

Cattle: 1 ml SC or IM

Sheep, Goats, Swine: 0.5 ml SC or IM

Historically, annual single dose revaccination has been recommended. Contact veterinarian for advice.

OTHER INFORMATION: Contains thimerosal and formalin as preservatives. Tetanus Toxoid Concentrate is available in single dose size packaged 10 vials to the carton, and in 10 dose vials.


VLN: 188 / PCN: 8601.00

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216


Contact us for information on other Colorado Serum Company products. Fine Veterinary Products since 1923.




Order #

10 - 1 ml vials

10 - 1 dose vials


10 ml

10 doses


CPN: 1101033.3



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