Once PMH IN

MERCK ANIMAL HEALTH
Intervet Inc.
2 GIRALDA FARMS, MADISON, NJ, 07940
Customer Service: 800-521-5767
Order Desk: 800-648-2118
Technical Service (Companion Animal): 800-224-5318
Technical Service (Livestock): 800-211-3573
Fax: 973-937-5557
Website: www.merck-animal-health-usa.com
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.
BOVILIS® Once PMH® IN

Intervet/Merck Animal Health

Mannheimia Haemolytica-Pasteurella Multocida Vaccine

Avirulent Live Culture

Cattle Vaccine

For Intranasal Use

This product has been shown effective for the vaccination of healthy cattle 1 week of age or older against disease due to Mannheimia haemolytica and Pasteurella multocida. Duration of immunity has not been established. For more information regarding efficacy and safety data, go to productdata.aphis.usda.gov.

DIRECTIONS: 1 Dose/10 Doses - Rehydrate freeze dried vial with accompanying vial of diluent. Mix reconstituted vial well and administer a single 1.0 mL dose aseptically into each nostril or 2.0 mL into only one nostril. Historically, annual revaccination with this product has been recommended. The need for this booster has not been established. For more information on revaccination frequency, consult your veterinarian.

MIXING DIRECTIONS: 50 Doses - Rehydrate freeze dried vial of Once PMH® IN with part of the accompanying vial of diluent using the transfer needle provided (see pictorial directions). Mix reconstituted vial well and transfer rehydrated vaccine into diluent vial using transfer needle. Remove transfer needle from former diluent vial and mix reconstituted vial well. Peel label from bottle of Once PMH® IN and place on diluent vial containing all vaccine.

USE DIRECTIONS: Administer a single 1.0 mL dose aseptically into each nostril or 2.0 mL into only one nostril. Historically, annual revaccination with this product has been recommended. The need for this booster has not been established. For more information on revaccination frequency, consult your veterinarian.

Mixing Instructions


CAUTION: THE TRANSFER NEEDLE, INCLUDED IN THE CARTON PACKAGING, IS SHARP AND MAY CAUSE INJURY TO SELF OR ANIMALS IF NOT HANDLED OR DISPOSED OF PROPERLY.

1. Insert the transfer needle fully into the small vial of dehydrated vaccine to release the vacuum.

2. Insert the other end of the transfer needle fully into the large vial of sterile diluent.

3. Squeeze enough diluent from the large bottle into the smaller vial to rehydrate the vaccine.

4. With the two bottles still attached, swirl the small vial gently until the vaccine is mixed.

5. With the small vial upside down, squeeze the large bottle several times to draw the mixed vaccine into the large bottle.

6. Separate the bottles and remove the vaccine label from the small vial and apply it to the large bottle for proper identification.

CAUTIONS: Store at 2 to 8°C (35 to 46°F). Do not freeze. Use entire contents when first opened. Do not mix with other products, except as specified on the label. Inactivate unused contents before disposal. Do not vaccinate within 21 days of slaughter. This product has not been tested in pregnant animals. Anaphylactoid reactions may occur following use. Antidote: Epinephrine. Contains streptomycin as a preservative. In case of human exposure, contact a physician.

FOR ANIMAL USE ONLY

Intervet Inc., d/b/a Merck Animal Health, Omaha, NE 68103, USA

VLN 165A/ PCN 1861.02

1-800-521-5767

For patent information:

http://www.merck.com/product/patent/home.html







Code



20 mL

10 Doses

2 mL per dose

117258

319364-04

25 x 1 Dose

25 Doses

156004

337673-02

100 mL

50 Doses

109221

352961-05

CPN: 1047567.0COLORADO SERUM COMPANY4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428Telephone: 303-295-7527Order Desk: 800-525-2065Fax: 303-295-1923Website: www.colorado-serum.comEmail: colorado-serum@colorado-serum.comTHIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.

TETANUS TOXOID-CONCENTRATED

Colorado Serum

Adjuvanted

GENERAL INFORMATION: This product has been shown to be effective for the vaccination of healthy horses, cattle, sheep, goats, and swine against tetanus. This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.

Safety in pregnant animals is unknown.

Tetanus Toxoid is prepared by detoxifying tetanus toxin in such a manner as to allow the antigenic properties to remain intact. Product is purified, concentrated and adjuvanted to provide a low dose effective immunizing agent.

Each serial is tested for purity, safety, and potency in accordance with USDA requirements.

Tetanus is caused by a neurotoxin produced by growth of Clostridium tetani, an anaerobic (lives without air) micro-organism, in necrotic tissue. Affected animals become stiff, have difficulty swallowing, and have an increased pulse rate. Breathing is labored. Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw.

Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw. Thus, the term “lockjaw” is often used. Legs and tail are often stiff with abdominal muscles contracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.

Protective antibody levels usually occur about two weeks after the second injection of the primary immunization series. In contrast, administration of Tetanus Antitoxin is recommended for immediate, emergency, passive treatment of exposed animals with unknown vaccination history or with signs of tetanus infection.

DIRECTIONS: Do not vaccinate within 21 days before slaughter. Store at 2-8° C. Do not freeze. Do not mix with other products. Shake well before use. Use entire contents when first opened.

PRECAUTIONS: A transitory local reaction may occur at injection site. Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. In case of human exposure, consult a physician.

DOSAGE & ADMINISTRATION: For primary immunization, two doses should be administered subcutaneously or intramuscularly approximately 30 days apart. Use intramuscularly for horses as local reactions are more likely to occur if injected subcutaneously.

Horses: 1 ml IM

Cattle: 1 ml SC or IM

Sheep, Goats, Swine: 0.5 ml SC or IM

Historically, annual single dose revaccination has been recommended. Contact veterinarian for advice.

OTHER INFORMATION: Contains thimerosal and formalin as preservatives. Tetanus Toxoid Concentrate is available in single dose size packaged 10 vials to the carton, and in 10 dose vials.

THE PEAK OF QUALITY SINCE 1923

VLN: 188 / PCN: 8601.00

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216

303-295-752

www.colorado-serum.com

Contact us for information on other Colorado Serum Company products. Fine Veterinary Products since 1923.

FOR VETERINARY USE ONLY

Order #

10 - 1 ml vials

10 - 1 dose vials

11411

10 ml

10 doses

11415

CPN: 1101033.3