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Zoetis

LitterGuard LT-C-50 Dose

LitterGuard LT-C-50 Dose

Regular price $58.95 USD
Regular price Sale price $58.95 USD
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Size: 50 Dose

For the vaccination of healthy, pregnant swine as an aid in passive maternal immunization of their pigs against neonatal diarrhea caused by Cl. perfringens Type C and E. coli bacteria.

Dosage: 2 ml IM or subcut to pregnant sows and gilts. 21-day slaughter withdrawal. 

Manufacturer and/or Label Information

ZOETIS INC.
333 PORTAGE STREET, KALAMAZOO, MI, 49007
Telephone: 269-359-4414
Customer Service: 888-963-8471
Website: www.zoetis.com
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.
LITTERGUARD® LT-C

Zoetis

Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid

U.S. Vet. Lic. No.: 190

Description: The bacterin-toxoid is prepared from chemically inactivated strains of E. coli and Cl. perfringens type C beta toxoid. A sterile adjuvant is used to enhance the immune response.

Indications: LITTERGUARD® LT-C is for vaccination of healthy pregnant sows and gilts for passive transfer of protective maternal antibodies to their pigs against neonatal diarrhea caused by beta toxin produced by Clostridium perfringens type C and enterotoxigenic strains of Escherichia coli producing heat-labile toxin or having the K99, K88, 987P, or F41 adherence factors.

Directions:

1. General Directions: Shake well. Aseptically administer 2 mL intramuscularly or subcutaneously.

2. Primary Vaccination: Healthy, pregnant swine should receive 2 doses administered 3 weeks apart during the last half of pregnancy. The second dose should be given at least 2 weeks before farrowing.

3. Revaccination: Pregnant swine should be revaccinated with a single dose at least 2 weeks before each subsequent farrowing.

4. Good animal husbandry and herd health management practices should be employed.

Precaution(s): Store at 2°-7°C. Prolonged exposure to higher temperatures may adversely affect potency. Do not freeze.

Use entire contents when first opened.

Sterilized syringes and needles should be used to administer this vaccine.

Caution(s): As with many vaccines, anaphylaxis may occur after use. Initial antidote of epinephrine is recommended and should be followed with appropriate supportive therapy.

This product has been shown to be efficacious in healthy animals. A protective immune response may not be elicited if animals are incubating an infectious disease, are malnourished or parasitized, are stressed due to shipment or environmental conditions, are otherwise immunocompromised, or the vaccine is not administered in accordance with label directions.

For veterinary use only.

Warning(s): Do not vaccinate within 21 days before slaughter.

Discussion: Disease Description: Enterotoxigenic strains of E. coli are among the most important etiologic agents of porcine neonatal diarrhea. Studies have shown that enterotoxigenic E. coli isolated from diarrheic pigs have 2 characteristics in common: (1) they have pili, surface antigenic structures which attach the bacteria to cells of the intestinal epithelium; and (2) they express enterotoxins, causing the intestinal cells to secrete body fluids and electrolytes into the gut lumen. The results are diarrhea, dehydration, and in severe cases, death. The 4 major pili types associated with neonatal enteric colibacillosis in swine are K99, K88, 987P,1 and F41.2

Cl. perfringens type C produces a highly fatal enteritis, usually in pigs less than 1 week old. It is characterized clinically by dehydration, weakness, and diarrhea, which is hemorrhagic in peracute and acute cases. Although morbidity rates vary greatly between herds and even between litters in the same herd, mortality is consistently high in pigs clinically affected. Death may be caused by one or more of the consequences of enterotoxemia. In some cases secondary bacteremia occurs, usually involving E. coli or other Cl. perfringens types.3

Trial Data: Safety and Efficacy: No adverse reactions to LITTERGUARD® LT-C were reported in experimental tests, or in clinical trials conducted by independent veterinarians. Efficacy of LITTERGUARD® LT-C was demonstrated in challenge-of-immunity tests involving pregnant sows and gilts and their litters. Newborn pigs from vaccinated dams experienced significantly lower incidence and severity of neonatal diarrhea than newborn pigs from nonvaccinated dams. No immunologic interference was demonstrated among the various fractions of LITTERGUARD® LT-C.

LITTERGUARD® LT-C protects pigs by means of maternally derived antibodies present in colostrum and milk of vaccinated dams. Newborn pigs' adequate and timely consumption of the colostrum and milk is therefore essential for protection.

References: Available upon request.

K88 component under Zoetis Inc. contract with Cetus Corporation.

75-4408-06

Presentation: 10 dose and 50 dose vials.

CPN: 3690055.3
COLORADO SERUM COMPANY4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428Telephone: 303-295-7527Order Desk: 800-525-2065Fax: 303-295-1923Website: www.colorado-serum.comEmail: colorado-serum@colorado-serum.comTHIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.

TETANUS TOXOID-CONCENTRATED

Colorado Serum

Adjuvanted

GENERAL INFORMATION: This product has been shown to be effective for the vaccination of healthy horses, cattle, sheep, goats, and swine against tetanus. This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.

Safety in pregnant animals is unknown.

Tetanus Toxoid is prepared by detoxifying tetanus toxin in such a manner as to allow the antigenic properties to remain intact. Product is purified, concentrated and adjuvanted to provide a low dose effective immunizing agent.

Each serial is tested for purity, safety, and potency in accordance with USDA requirements.

Tetanus is caused by a neurotoxin produced by growth of Clostridium tetani, an anaerobic (lives without air) micro-organism, in necrotic tissue. Affected animals become stiff, have difficulty swallowing, and have an increased pulse rate. Breathing is labored. Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw.

Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw. Thus, the term “lockjaw” is often used. Legs and tail are often stiff with abdominal muscles contracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.

Protective antibody levels usually occur about two weeks after the second injection of the primary immunization series. In contrast, administration of Tetanus Antitoxin is recommended for immediate, emergency, passive treatment of exposed animals with unknown vaccination history or with signs of tetanus infection.

DIRECTIONS: Do not vaccinate within 21 days before slaughter. Store at 2-8° C. Do not freeze. Do not mix with other products. Shake well before use. Use entire contents when first opened.

PRECAUTIONS: A transitory local reaction may occur at injection site. Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. In case of human exposure, consult a physician.

DOSAGE & ADMINISTRATION: For primary immunization, two doses should be administered subcutaneously or intramuscularly approximately 30 days apart. Use intramuscularly for horses as local reactions are more likely to occur if injected subcutaneously.

Horses: 1 ml IM

Cattle: 1 ml SC or IM

Sheep, Goats, Swine: 0.5 ml SC or IM

Historically, annual single dose revaccination has been recommended. Contact veterinarian for advice.

OTHER INFORMATION: Contains thimerosal and formalin as preservatives. Tetanus Toxoid Concentrate is available in single dose size packaged 10 vials to the carton, and in 10 dose vials.

THE PEAK OF QUALITY SINCE 1923

VLN: 188 / PCN: 8601.00

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216

303-295-752

www.colorado-serum.com

Contact us for information on other Colorado Serum Company products. Fine Veterinary Products since 1923.

FOR VETERINARY USE ONLY

 

 

Order #

10 - 1 ml vials

10 - 1 dose vials

11411

10 ml

10 doses

11415

CPN: 1101033.3

Dimensions

Care information

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