Express® 5- HS - 10 Dose is for the vaccination of healthy, susceptible cattle as an aid in the reduction of respiratory diseases caused by Bovine Rhinotracheitis (IBR) virus, Bovine Virus Diarrhea (BVD) Types 1 and 2, Parainfluenza 3 (PI3) virus, and Bovine Respiratory Syncytial Virus (BRSV), and as an aid in the prevention of disease caused by Haemophilus somnus. This vaccine may be used in pregnant females or calves nursing pregnant females, provided the females were vaccinated pre-breeding according to label directions with any Express® FP vaccine. Modified-live virus for vaccination of healthy, susceptible cattle as an aid in prevention of respiratory disease caused by IBR, BVD Types 1 and 2, and BRSV; as an aid in reduction of respiratory disease caused by PI3; and as an aid in prevention of disease caused by Haemophilus somnus.
Store out of direct sunlight at 35-46°F (2-8°C). Do not freeze. Do not mix with other products, except as specified on the label. Use entire contents when first opened. Do not vaccinate within 21 days before slaughter. Injection site swelling may occur. Stressed cattle should not be vaccinated. In case of anaphylactoid reaction, administer epinephrine. In case of human exposure, contact a physician. Inactivate unused contents before disposal.
Fetal health risks associated with vaccination of pregnant animals with this vaccine cannot be unequivocally determined by clinical trials conducted for licensure. Appropriate strategies to address the risks associated with vaccine use in pregnant animals should be discussed with a veterinarian. No vaccine can be expected to have 100% efficacy under all conditions. A small number of calves persistently infected with BVD may have a devastating effect on herd health.
Dosage: 2 ml subcut. If initial vaccination, repeat with any Express vaccine containing BRSV modified-live virus and H. somnus in 14-28 days. Calves vaccinated before 6 months of age should be revaccinated at 6 months. Revaccinate annually. May be used in pregnant females or calves nursing pregnant females, provided the females were vaccinated pre-breeding according to label directions with any Express FP vaccine. 21 day slaughter withdrawal.
Note: It is possible that healthy-appearing cattle can be persistently infected with or incubating virulent BVD virus at the time of vaccination. In view of these findings and suggested causes, BVD vaccine is contraindicated in persistently infected cattle and use should be limited only to healthy, immunocompetent, unstressed cattle.
Manufacturer and/or Label Information
Manufacturer and/or Label Information
GENERAL INFORMATION: This product has been shown to be effective for the vaccination of healthy horses, cattle, sheep, goats, and swine against tetanus. This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.
Safety in pregnant animals is unknown.
Tetanus Toxoid is prepared by detoxifying tetanus toxin in such a manner as to allow the antigenic properties to remain intact. Product is purified, concentrated and adjuvanted to provide a low dose effective immunizing agent.
Each serial is tested for purity, safety, and potency in accordance with USDA requirements.
Tetanus is caused by a neurotoxin produced by growth of Clostridium tetani, an anaerobic (lives without air) micro-organism, in necrotic tissue. Affected animals become stiff, have difficulty swallowing, and have an increased pulse rate. Breathing is labored. Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw.
Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw. Thus, the term “lockjaw” is often used. Legs and tail are often stiff with abdominal muscles contracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.
Protective antibody levels usually occur about two weeks after the second injection of the primary immunization series. In contrast, administration of Tetanus Antitoxin is recommended for immediate, emergency, passive treatment of exposed animals with unknown vaccination history or with signs of tetanus infection.
DIRECTIONS: Do not vaccinate within 21 days before slaughter. Store at 2-8° C. Do not freeze. Do not mix with other products. Shake well before use. Use entire contents when first opened.
PRECAUTIONS: A transitory local reaction may occur at injection site. Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. In case of human exposure, consult a physician.
DOSAGE & ADMINISTRATION: For primary immunization, two doses should be administered subcutaneously or intramuscularly approximately 30 days apart. Use intramuscularly for horses as local reactions are more likely to occur if injected subcutaneously.
Horses: 1 ml IM
Cattle: 1 ml SC or IM
Sheep, Goats, Swine: 0.5 ml SC or IM
Historically, annual single dose revaccination has been recommended. Contact veterinarian for advice.
OTHER INFORMATION: Contains thimerosal and formalin as preservatives. Tetanus Toxoid Concentrate is available in single dose size packaged 10 vials to the carton, and in 10 dose vials.
THE PEAK OF QUALITY SINCE 1923
VLN: 188 / PCN: 8601.00
COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216
Contact us for information on other Colorado Serum Company products. Fine Veterinary Products since 1923.
FOR VETERINARY USE ONLY
10 - 1 ml vials
10 - 1 dose vials