333 PORTAGE STREET, KALAMAZOO, MI, 49007
Customer Service: 888-963-8471
(progesterone and estradiol benzoate implants)
100 mg progesterone and 10 mg estradiol benzoate per implant
For increased rate of weight gain
This product was manufactured by a non-sterilizing process.
Important: Read ALL sides of carton
Do Not Use In Veal Calves
Not For Use In Humans
For Animal Use Only
For subcutaneous ear implantation only.
Approved by FDA under NADA # 009-576
Synovex C Calf Implants contain two pure steroid hormones, progesterone and estradiol benzoate. This formulation provides a complementary amount of each hormone for maximal growth stimulation. Study the enclosed instructions carefully and use this product only as illustrated.
HOW TO IMPLANT WITH SYNOVEX® C
(progesterone and estradiol benzoate)
100 mg progesterone and 10 mg estradiol benzoate per implant
Study the following instructions carefully, then proceed step by step, until the technique becomes routine. Many head can be implanted per hour by an experienced team, one member of which should be assigned to do nothing but the implantation. This person should maintain hand cleanliness and use sanitary instruments only.
SYNOVEX® C Implants
Synovex C (progesterone and estradiol benzoate implants) is recommended for use in suckling beef calves up to 400 lbs of body weight. Synovex C is also recommended for improvement in rate of weight gain in steers weighing greater than 400 pounds and fed in confinement for slaughter when used as part of a re-implant program in which an initial Synovex C implant is followed at approximately 70 days by Synovex S. Do not use in veal calves. Effectiveness and animal safety in veal calves have not been established.
Do not use in bull calves intended for reproduction, or in calves less than 45 days old.
Store at controlled room temperature 20° - 25°C (68° - 77°F) with excursions between 15°-30°C (59°-86°F). Avoid excessive heat or humidity.
Not for use in humans. For animal use only. Implant pellets in the ear only. Any other location is in violation of federal law. Do not attempt salvage of implanted site for human or animal food.
A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.
Bulling, rectal and vaginal prolapse, udder development, ventral edema and elevated tailheads may be reported in calves administered Synovex C implants.
Keep this and all drugs out of the reach of children.
Restricted Drug (California) - Use Only as Directed.
DIRECTIONS: Implant complete contents of one cartridge cell per calf at each implanting. Approved implantation technique is fully described in the package insert.
NOTE: Never sacrifice careful, clean technique for speed of implantation.
STEP 1 Loading the Applicator
Load the applicator following the directions outlined in the instruction manual accompanying each applicator.
Additional information for the individual applicator user guides can be found at: www.growwithsynovex.com.
STEP 2 Restraint
The animal must be confined in a restraint mechanism (squeeze chute or head gate). The implant site on the back of the ear should be prepared by scrubbing with a firm bristled brush that has been soaked in a germicidal solution.
Note: If implanting horned cattle, greater safety is provided when the head is controlled by the use of a bull lead (nose tongs).
STEP 3 Implant Site
Divide the ear into three imaginary sections as illustrated. The implanted pellets should be deposited in the center one-third of the ear as shown. To accomplish this, the applicator needle should be inserted in the outer one-third of the ear as indicated by the “X” in the illustration. Implanting too close to the head may cause abnormal sexual behavior. Care should be taken to avoid severing the major arteries of the ear.
STEP 4 Insert Needle
Grasp the ear with one hand. While holding the applicator firmly with the other hand, penetrate the skin at the point shown by the “X”. Thrust the needle under the skin taking care not to penetrate the cartilage. Ease the applicator forward (toward the base of the ear) until the full needle length is beneath the skin.
STEP 5 Pellet Implantation
When the needle is completely inserted, activate the instrument by squeezing the trigger completely. Refer to instructions for individual applicator.
STEP 6 Inspection
Check the implant site. If properly administered, the implants should lie in a straight line under the skin.
Re-cock the applicator. Disinfect the applicator needle in a germicidal solution. The applicator is now ready to implant the next animal.
Distributed by: Zoetis Inc., Kalamazoo, MI 49007
10 CARTRIDGES (100 DOSES)
Each Cartridge Contains 10 Rows of 4 Pellets.
GENERAL INFORMATION: This product has been shown to be effective for the vaccination of healthy horses, cattle, sheep, goats, and swine against tetanus. This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.
Safety in pregnant animals is unknown.
Tetanus Toxoid is prepared by detoxifying tetanus toxin in such a manner as to allow the antigenic properties to remain intact. Product is purified, concentrated and adjuvanted to provide a low dose effective immunizing agent.
Each serial is tested for purity, safety, and potency in accordance with USDA requirements.
Tetanus is caused by a neurotoxin produced by growth of Clostridium tetani, an anaerobic (lives without air) micro-organism, in necrotic tissue. Affected animals become stiff, have difficulty swallowing, and have an increased pulse rate. Breathing is labored. Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw.
Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw. Thus, the term “lockjaw” is often used. Legs and tail are often stiff with abdominal muscles contracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.
Protective antibody levels usually occur about two weeks after the second injection of the primary immunization series. In contrast, administration of Tetanus Antitoxin is recommended for immediate, emergency, passive treatment of exposed animals with unknown vaccination history or with signs of tetanus infection.
DIRECTIONS: Do not vaccinate within 21 days before slaughter. Store at 2-8° C. Do not freeze. Do not mix with other products. Shake well before use. Use entire contents when first opened.
PRECAUTIONS: A transitory local reaction may occur at injection site. Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. In case of human exposure, consult a physician.
DOSAGE & ADMINISTRATION: For primary immunization, two doses should be administered subcutaneously or intramuscularly approximately 30 days apart. Use intramuscularly for horses as local reactions are more likely to occur if injected subcutaneously.
Horses: 1 ml IM
Cattle: 1 ml SC or IM
Sheep, Goats, Swine: 0.5 ml SC or IM
Historically, annual single dose revaccination has been recommended. Contact veterinarian for advice.
OTHER INFORMATION: Contains thimerosal and formalin as preservatives. Tetanus Toxoid Concentrate is available in single dose size packaged 10 vials to the carton, and in 10 dose vials.
THE PEAK OF QUALITY SINCE 1923
VLN: 188 / PCN: 8601.00
COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216
Contact us for information on other Colorado Serum Company products. Fine Veterinary Products since 1923.
FOR VETERINARY USE ONLY
10 - 1 ml vials
10 - 1 dose vials