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Merck Animal Health

Matrix Solution for Mature Gilts

Matrix Solution for Mature Gilts

Regular price $201.99 USD
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***Item cannot be shipped to California***
For synchronization of estrus (standing heat) in sexually mature gilts that have had at least one estrous cycle. Can enhance profitability by creating a predictable breeding timetable for gilts, and reducing heat checking. Helps improve operational efficiency due to unparalleled control of estrus synchronization.

Active ingredient: Altrenogest solution 0.22% (2.2 mg/ml).

Dosage: Administer 6.8 ml per gilt once daily for 14 consecutive days on an individual basis by top-dressing on a portion of daily feed allowance. Do not use in gilts having previous or current history of uterine inflammation. 21 day slaughter withdrawal.

Important notes: Use protective gloves while handling. Draw out appropriate volume with just a luer lock syringe, no needle.
Size: 1000 mL

Manufacturer and/or Label Information

MERCK ANIMAL HEALTH
Intervet Inc.
2 GIRALDA FARMS, MADISON, NJ, 07940
Customer Service: 800-521-5767
Order Desk: 800-648-2118
Technical Service (Companion Animal): 800-224-5318
Technical Service (Livestock): 800-211-3573
Fax: 973-937-5557
Website: www.merck-animal-health-usa.com
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.
MATRIX®

Intervet/Merck Animal Health

(altrenogest)

Oral solution, 2.2 mg altrenogest per mL (0.22%)

Synthetic progestin

For Use in Swine Only

USES:

For synchronization of estrus in sexually mature gilts that have had at least one estrous cycle. Treatment with MATRIX® results in estrus (standing heat) 4 to 9 days after completion of the 14-day treatment period.

It is a violation of Federal law to use this drug product other than as directed in the labeling or as directed by your veterinarian.

DESCRIPTION:

MATRIX® (altrenogest) Oral Solution contains 2.2 mg altrenogest per mL (0.22%) in an oil solution.

WARNINGS:


WITHDRAWAL PERIODS

Animals intended for human consumption must not be slaughtered within 21 days of the last treatment with this drug product.


USER SAFETY WARNINGS:

Not for use in humans. Keep out of reach of children.

Skin contact must be avoided as MATRIX® is readily absorbed through unbroken skin, and exposure may result in serious side effects to both women and men. Always wear vinyl, neoprene, or nitrile protective gloves when handling MATRIX or when in contact with equipment or surfaces contaminated by this product. Latex gloves are not protective.

PREGNANT WOMEN OR WOMEN WHO MAY BE PREGNANT SHOULD NOT HANDLE MATRIX® (altrenogest). WOMEN OF CHILDBEARING AGE SHOULD EXERCISE EXTREME CAUTION WHEN HANDLING THIS PRODUCT.

Accidental absorption, such as absorption through the skin, could lead to a disruption of the menstrual cycle or prolongation of pregnancy.Wash off accidental spillage on the skin immediately with soap and water. Any equipment or surfaces that come in contact with MATRIX® should be adequately cleaned and decontaminated to prevent human exposure.

Always use the MATRIX® Dosing Device to administer this product. The MATRIX® bottle is designed only for use with the MATRIX® Dosing Device. Use without the device increases the risk of human exposure.

PEOPLE WHO SHOULD NOT HANDLE MATRIX®:*

1. Women who are or may be pregnant.

2. Anyone with blood clots or clotting disorders, or with a history of these events.

3. Anyone with a history of heart disease or stroke.

4. Women with known or suspected breast cancer.

5. People with known or suspected estrogen-dependent cancer.

6. Women with vaginal bleeding of unknown cause.

7. People with tumors which developed during the use of oral contraceptives or other estrogen-containing products.

8. Anyone with liver dysfunction or disease.

*Based on known effects of long-term progestin use in humans.

ACCIDENTAL EXPOSURE:

MATRIX® is readily absorbed from contact with the skin. In addition, this oil-based product can penetrate latex or other types of porous gloves.

Always wear vinyl, neoprene, or nitrile protective gloves when handling MATRIX®. Latex gloves are not protective. If MATRIX® gets inside gloves by damage or spilling, the covered skin may absorb more of the drug. Side effects after a single exposure are possible; however, continued daily exposure has the potential for more serious effects.

IN CASE OF ACCIDENTAL EXPOSURE:

Skin exposure and/or clothing contamination: Wash skin immediately with soap and water, and launder clothing with detergent.

Eye exposure: Immediately flush with plenty of water for 15 minutes. Get medical attention. If wearing contact lenses, flush eyes immediately with water before removing lenses.

If swallowed: Do not induce vomiting. Seek medical attention immediately. MATRIX® contains an oil. Vomiting should be supervised by a physician because of possible pulmonary damage via aspiration of the oil base. If possible, bring the labeling to the physician.

Reported HUMAN Effects from Exposure:

Side effects have been reported in women and men following accidental exposure to altrenogest products, including MATRIX®, either through handling of the product or contact with contaminated surfaces.

• Reproductive side effects reported in women included abnormal or absent menstrual cycles.

• Reproductive side effects in men included decreased libido.

• Other side effects reported in women and men included headaches, fever, abdominal pain, nausea, diarrhea, vomiting, and rashes.

ANIMAL SAFETY WARNINGS:

Do not use MATRIX® in gilts having a previous or current history of uterine inflammation (i.e., acute, subacute, or chronic endometritis).

Underdosing of MATRIX® may lead to the occurrence of cystic follicles.

OTHER EFFECTS YOU MAY NOTICE:

A small percentage (less than 5%) of treated gilts may exhibit estrus (standing heat) during the 14-day treatment period. Gilts nearing estrus at the start of the 14-day treatment period may express estrus early in that period.

DIRECTIONS:

While wearing vinyl, neoprene, or nitrile gloves, remove shipping cap and seal; replace with enclosed plastic dispensing cap. This product can penetrate latex or other types of porous gloves. Latex gloves are not protective. Connect the MATRIX® Dosing Device to the solution bottle, according to the instructions provided with the MATRIX® Dosing Device package. Do not use any dosing device other than the MATRIX® Dosing Device.

Administer 6.8 mL (15 mg altrenogest) per gilt once daily for 14 consecutive days. Treat gilts on an individual animal basis by top-dressing MATRIX® on a portion of each gilt’s daily feed allowance. To produce the desired synchronization of estrus in a group of gilts, treat all of the gilts daily for the same 14-day period.

HOW SUPPLIED:

MATRIX® (altrenogest) Oral Solution contains 2.2 mg/mL (0.22%) of the active ingredient, packaged in 1,000 mL plastic bottles.

STORAGE, HANDLING, AND DISPOSAL:

Store MATRIX® solution bottle and Dosing Device when loaded with solution for continued use at or below room temperature, 77°F (25°C). Close tightly. Refer to the MATRIX® Dosing Device label for equipment cleaning instructions. Place empty drug containers, waste from rinsing the Dosing Device, protective gloves, or other articles that contact this product in a leak-resistant container for disposal in accordance with applicable Federal, state, and local regulations.

QUESTIONS? COMMENTS?

• To report side effects, contact Merck at 1-800-211-3573, or online at www.merck-animal-health-usa.com

• To obtain product information, including a safety data sheet (SDS), call 1-800-441-8272.

• For additional information about reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or online at: www.fda.gov/reportanimalae

Approved by FDA under NADA # 141-222

Restricted Drug (California) - use only as directed.

Manufactured for: Intervet Inc. (d/b/a Merck Animal Health), Madison, NJ 07940, a subsidiary of Merck & Co.

Made in France.

Net Contents:



1,000 mL (33.8 fl. oz.)

Rev. 8/2022

336663 R8

CPN: 1047347.4



COLORADO SERUM COMPANY4950 YORK STREET, P.O. BOX 16428, DENVER, CO, 80216-0428Telephone: 303-295-7527Order Desk: 800-525-2065Fax: 303-295-1923Website: www.colorado-serum.comEmail: colorado-serum@colorado-serum.comTHIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.

TETANUS TOXOID-CONCENTRATED

Colorado Serum

Adjuvanted

GENERAL INFORMATION: This product has been shown to be effective for the vaccination of healthy horses, cattle, sheep, goats, and swine against tetanus. This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.

Safety in pregnant animals is unknown.

Tetanus Toxoid is prepared by detoxifying tetanus toxin in such a manner as to allow the antigenic properties to remain intact. Product is purified, concentrated and adjuvanted to provide a low dose effective immunizing agent.

Each serial is tested for purity, safety, and potency in accordance with USDA requirements.

Tetanus is caused by a neurotoxin produced by growth of Clostridium tetani, an anaerobic (lives without air) micro-organism, in necrotic tissue. Affected animals become stiff, have difficulty swallowing, and have an increased pulse rate. Breathing is labored. Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw.

Spasmodic contractions of the muscular system occur, such as contracting muscles of the jaw. Thus, the term “lockjaw” is often used. Legs and tail are often stiff with abdominal muscles contracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.

Protective antibody levels usually occur about two weeks after the second injection of the primary immunization series. In contrast, administration of Tetanus Antitoxin is recommended for immediate, emergency, passive treatment of exposed animals with unknown vaccination history or with signs of tetanus infection.

DIRECTIONS: Do not vaccinate within 21 days before slaughter. Store at 2-8° C. Do not freeze. Do not mix with other products. Shake well before use. Use entire contents when first opened.

PRECAUTIONS: A transitory local reaction may occur at injection site. Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. In case of human exposure, consult a physician.

DOSAGE & ADMINISTRATION: For primary immunization, two doses should be administered subcutaneously or intramuscularly approximately 30 days apart. Use intramuscularly for horses as local reactions are more likely to occur if injected subcutaneously.

Horses: 1 ml IM

Cattle: 1 ml SC or IM

Sheep, Goats, Swine: 0.5 ml SC or IM

Historically, annual single dose revaccination has been recommended. Contact veterinarian for advice.

OTHER INFORMATION: Contains thimerosal and formalin as preservatives. Tetanus Toxoid Concentrate is available in single dose size packaged 10 vials to the carton, and in 10 dose vials.

THE PEAK OF QUALITY SINCE 1923

VLN: 188 / PCN: 8601.00

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216

303-295-752

www.colorado-serum.com

Contact us for information on other Colorado Serum Company products. Fine Veterinary Products since 1923.

FOR VETERINARY USE ONLY

 

 

Order #

10 - 1 ml vials

10 - 1 dose vials

11411

10 ml

10 doses

11415

CPN: 1101033.3

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